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EGF Protein (AA 974-1026)

EGF Spezies: Ratte Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2017760
  • Target Alle EGF Proteine anzeigen
    EGF (Epidermal Growth Factor (EGF))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 974-1026
    Spezies
    • 22
    • 13
    • 7
    • 4
    • 3
    • 1
    Ratte
    Quelle
    • 32
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    CHO Cells
    Produktmerkmale
    ED50 < 0.1 ng/mL, measured in a cell proliferation assay using 3T3 cells.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Rat Epidermal Growth Factor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Rat Epidermal Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    EGF (Epidermal Growth Factor (EGF))
    Abstract
    EGF Produkte
    Synonyme
    HOMG4 Protein, URG Protein, AI790464 Protein, CEGF Protein, epidermal growth factor Protein, pro-epidermal growth factor Protein, EGF Protein, egf Protein, CpipJ_CPIJ020278 Protein, Egf Protein
    Hintergrund
    Epidermal Growth Factor, a low-molecular-weight polypeptide, is the founding member of the EGF-family of proteins. It can be found in platelets, macrophages, urine, saliva, etc. EGF acts by binding with high affinity to the Epidermal Growth Factor Receptor (EGFR) and stimulating downstream protein tyrosine kinase activity. This signal transduction cascade results in increased intracellular calcium levels and increased rates of glycolysis and protein synthesis. EGF stimulates the growth of many epidermal and epithelial tissues. Pharmaceutical drugs designed to inhibit EGFR have been used to treat certain types of cancer.
    Synonyms: Epidermal Growth Factor, Urogastrone, URG
    Molekulargewicht
    6 kDa, observed by reducing SDS-PAGE.
    UniProt
    P07522
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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