FGF18 Protein (AA 27-199)

Produktnummer ABIN2017815

Produktdetails

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 27-199

Spezies: Human

Quelle: Escherichia coli (E. coli)

Produktmerkmale: ED50 < 10 ng/mL, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 1.0x 105 units/mg.
AA 27 -199, expressed with an N-terminal Met.

Reinheit: > 95 % by SDS-PAGE and HPLC analyses.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: FGF18 (Fibroblast Growth Factor 18 (FGF18))

Andere Bezeichnung: Fibroblast Growth Factor-18 (FGF-18) (FGF18 Produkte)

Synonyme: FGF-18 Protein, ZFGF5 Protein, D130055P09Rik Protein, fgf18 Protein, FGF18 Protein, fgf18l Protein, fibroblast growth factor 18 Protein, fibroblast growth factor 18a Protein, fibroblast growth factor 18b Protein, FGF18 Protein, Fgf18 Protein, fgf18a Protein, Tsp_09844 Protein, fgf18b Protein

Hintergrund: Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-18, zFGF5, FGFI

Molekulargewicht: 20.3 kDa, observed by reducing SDS-PAGE.

UniProt: O76093

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung