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G-CSF Protein (AA 31-208)

Dieses Recombinant G-CSF-Protein wird in CHO Cells exprimiert.
Produktnummer ABIN2017898

Kurzübersicht für G-CSF Protein (AA 31-208) (ABIN2017898)

Target

Alle G-CSF (CSF3) Proteine anzeigen
G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 26
  • 9
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Maus

Quelle

  • 24
  • 11
  • 5
  • 2
  • 2
  • 1
  • 1
CHO Cells

Reinheit

> 95 % as analyzed by SDS-PAGE and HPLC.
  • Proteineigenschaft

    AA 31-208

    Produktmerkmale

    ED50 <0.02 ng/mL, measured in a cell proliferation assay using NFS-60 cells.

    Endotoxin-Niveau

    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Lyophilized recombinant murine G-CSF remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, murine G-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.

    Haltbarkeit

    6 months
  • Target

    G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

    Andere Bezeichnung

    Granulocyte Colony-Stimulating Factor (G-CSF)

    Hintergrund

    Granulocyte Colony-Stimulating Factor (G-CSF), also known as CSF-3 and MGI-1G, is a cytokine and hormone belonging to the IL-6 superfamily. It is expressed by monocytes, macrophages, endothelial cells, fibroblasts and bone marrow stroma. G-CSF stimulates the bone marrow to produce granulocytes and stem cells, and specifically stimulates the proliferation and differentiation of the neutrophilic granulocyte lineage. G-CSF has been used to stimulate white blood cell production after chemotherapy. It has also been used to boost the number of hematopoietic stem cells after bone marrow transplantation.
    Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFb, pluripoietin

    Molekulargewicht

    22-24 kDa, observed by reducing SDS-PAGE.

    UniProt

    P09920

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
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