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IFNW1 Protein

IFNW Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS-PAGE and HPLC analyses. Active
Produktnummer ABIN2017994
  • Target Alle IFNW1 (IFNW) Proteine anzeigen
    IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequenz
    CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
    Produktmerkmale
    Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/mL, corresponding to a specific activity of > 1.0 x 10^8 IU/mg.
    Reinheit
    > 97 % by SDS-PAGE and HPLC analyses.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    < 1 EU/μg of rHuIFN-μ as determined by LAL method.
    Top Product
    Discover our top product IFNW Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Buffer
    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
  • Target
    IFNW1 (IFNW) (Interferon, omega 1 (IFNW))
    Andere Bezeichnung
    Interferon omega (IFNW Produkte)
    Synonyme
    IFNW1 Protein, interferon omega 1 Protein, interferon, omega 1 Protein, inteferon omega 1 Protein, IFNW1 Protein, LOC100155760 Protein, IFN-OMEGA1 Protein
    Hintergrund
    Interferon-Omega (IFN-o) coded by IFNW1 gene in human, is a number of the type I interferon family, which includes IFN-a, IFN-b, and IFN-o. The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction, followed the antiviral or the antiproliferative actions. IFN-omega is derived from IFN-a/b and share 75 % sequence with IFN-a. It has two intramolecular disulfide bonds which are crucial for activities. Mire-Sluis et al have described bioassays for IFN-a, IFN-b, and IFN-o that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF. The bioassays can be used also with Epo and TF-1 cells, or Epo and Epo-transfected UT-7 cells.
    Synonyms: IFN Omega Human
    Molekulargewicht
    20.0 kDa, containing 172 amino acid residues with two conserved disulfide bonds.
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