IL13
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by SDS-PAGE
WB, ELISA
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstituted in ddH2O or PBS at 100 μg/mL.
Buffer
Lyophilized after extensive dialysis against PBS.
Lagerung
-80 °C
Informationen zur Lagerung
Lyophilized recombinant human Interleukin 13 (IL-13) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-13 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
Interleukin 13 (IL-13) is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and mouse IL-13 is cross-species reactive.Recombinant human interleukin 13 expressed in CHO cells is glycosylated protein with molecular weight range from 25 to 45 kDa shown in non-reducing SDS-PAGE. Synonyms: NC30 (Human), P600 (Murine),IL-13 (human)