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IL-3 Protein (AA 20-152)

IL-3 Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018017
  • Target Alle IL-3 Proteine anzeigen
    IL-3 (Interleukin 3 (IL-3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 20-152
    Spezies
    • 21
    • 12
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 27
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    CHO Cells
    Produktmerkmale
    ED50 < 0.1 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1x10^7 units/mg.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant human Interlerkin 3 (IL-3) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-3 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    IL-3 (Interleukin 3 (IL-3))
    Abstract
    IL-3 Produkte
    Synonyme
    BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
    Hintergrund
    Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.Recombinant human interleukin 3 expressed in CHO cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE.
    Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
    Molekulargewicht
    17-30 kDa, observed by non-reducing SDS-PAGE.
    UniProt
    Q6GS87
    Pathways
    JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
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