IL-3 Protein (AA 20-152)
Kurzübersicht für IL-3 Protein (AA 20-152) (ABIN2018017)
Target
Alle IL-3 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
-
-
Proteineigenschaft
- AA 20-152
-
Produktmerkmale
- ED50 < 0.1 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1x10^7 units/mg.
-
Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
-
-
Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
-
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
-
Buffer
- Lyophilized after extensive dialysis against PBS.
-
Lagerung
- -80 °C
-
Informationen zur Lagerung
- Lyophilized recombinant human Interlerkin 3 (IL-3) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-3 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
-
Haltbarkeit
- 6 months
-
-
- IL-3 (Interleukin 3 (IL-3))
-
Hintergrund
-
Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.Recombinant human interleukin 3 expressed in CHO cells is glycosylated protein with molecular weight range from 17 to 30 kDa shown in non-reducing SDS-PAGE.
Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor -
Molekulargewicht
- 17-30 kDa, observed by non-reducing SDS-PAGE.
-
UniProt
- Q6GS87
-
Pathways
- JAK-STAT Signalweg, Regulation of Carbohydrate Metabolic Process, Autophagie
Target
-