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IL-9 Protein (AA 19-144)

IL9 Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018029
  • Target Alle IL-9 (IL9) Proteine anzeigen
    IL-9 (IL9) (Interleukin 9 (IL9))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 19-144
    Spezies
    • 14
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 15
    • 11
    • 4
    • 1
    • 1
    CHO Cells
    Produktmerkmale
    ED50 < 1 ng/mL, measured in a cell proliferation assay using MO7e cells, corresponding to a specific activity of > 1x10^6 units/mg.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant human Interlerkin 9 (IL-9) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-9 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    IL-9 (IL9) (Interleukin 9 (IL9))
    Andere Bezeichnung
    Interleukin 9 (IL-9) (IL9 Produkte)
    Synonyme
    IL9 Protein, IL-9 Protein, Il-9 Protein, P40 Protein, HP40 Protein, interleukin 9 Protein, IL9 Protein, il9 Protein, Il9 Protein
    Hintergrund
    Interleukin 9, also known as IL9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. The protein encoded by this gene is a cytokine produced by T-cells and specifically by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
    Synonyms: p40 cytokine, T-cell growth factor p40
    Molekulargewicht
    25-40 kDa, observed by non-reducing SDS-PAGE.
    UniProt
    P15248
    Pathways
    JAK-STAT Signalweg
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