IL18BP Protein (AA 31-194)
-
- Target Alle IL18BP Proteine anzeigen
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 31-194
-
Spezies
- Human
-
Quelle
- CHO Cells
- Produktmerkmale
- ED50 < 30 ng /mL, measured in a bioassay using KG-1 cells in the presence of 50 ng/mL Human IL-18.
- Reinheit
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL18BP Protein
-
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (Fc Tag)
IL18BP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His tag)IL18BP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His-Avi Tag,Biotin)IL18BP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (His tag)IL18BP Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (Fc Tag)IL18BP Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (GST tag)IL18BP Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 18 Binding Protein (IL18BP) proteinIL18BP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS
Interleukin 18 Binding Protein (IL18BP) (AA 31-192) protein (Fc Tag)IL18BP Spezies: Hund Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 18 Binding Protein (IL18BP) (AA 28-207) protein (Fc Tag)IL18BP Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant Human IL-18BP remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human IL-18BP should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
-
- Target
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Andere Bezeichnung
- Interleukin-18 Binding Protein (IL-18 BP) (IL18BP Produkte)
- Synonyme
- IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
- Hintergrund
-
Interleukin-18 binding protein, also known as IL-18BP and tadekinig-alfa, is a secreted glycoprotein that contains an Ig-like C2-type domain. It is expressed in heart, lung, placenta and spleen. IL-18BP functions as an inhibitor of the proinflammatory cytokine IL-18. It binds to IL-18, prevents the binding of IL-18 to its receptor, and thus blocks IL-18-induced IFN-gamma production. The complete Ig domain has been shown to mediate the binding and neutralizing properties. IFN-gamma is able to upregulate the expression of IL-18BP, indicating that IL-18 activity is regulated by a feedback mechanism through IL-18BP.
Synonyms: Tadekinig-alfa, IL18BP - Molekulargewicht
- 42-44 kDa, observed by reducing SDS-PAGE.
- UniProt
- O95998
-
