IL-8 Protein (AA 23-99)
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- Target Alle IL-8 (IL8) Proteine anzeigen
- IL-8 (IL8) (Interleukin 8 (IL8))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 23-99
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Spezies
- Human
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Quelle
- CHO Cells
- Produktmerkmale
- ED50 < 6 ng/mL, measured in a calcium flux assay using CHO/G alpha 15 cells transiently expressing CXCR1.
- Reinheit
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL8 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant Human Interleukin-8 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-8 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- IL-8 (IL8) (Interleukin 8 (IL8))
- Andere Bezeichnung
- Interleukin-8 (IL-8) (IL8 Produkte)
- Hintergrund
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Interleukin-8 (IL-8), also known as CXCL8, GCP-1 and NAP-1, is a proinflammatory chemokine belonging to the intercrine alpha (chemokine CXC) family. It is secreted by monocytes, macrophages and endothelial cells. IL-8 signals through CXCR1 and CXCR2 to chemoattract neutrophils, basophils, and T cells. IL-8 is also a potent promoter of angiogenesis. Other functions of this protein, such as involvement in bronchiolitis pathogenesis, have also been reported.
Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 - Molekulargewicht
- 38-40 kDa, observed by reducing SDS-PAGE.
- UniProt
- P10145
- Pathways
- TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
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