NGFR Protein (AA 29-250)

Produktnummer ABIN2018287

Produktdetails

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: AA 29-250

Spezies: Human

Quelle: HEK-293T Cells

Produktmerkmale: ED50 < 0.4 μg /mL, measured in a neutrolization assay using TF-1 cells in the presence of 10 ng/mL human b-NGF.

Reinheit: > 95 % as analyzed by SDS-PAGE.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human NGF Receptor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Andere Bezeichnung: NGF Receptor (NGFR Produkte)

Synonyme: ngfr Protein, wu:fb38c02 Protein, wu:fc10h01 Protein, CD271 Protein, Gp80-LNGFR Protein, TNFRSF16 Protein, p75(NTR) Protein, p75NTR Protein, LNGFR Protein, RNNGFRR Protein, Tnfrsf16 Protein, p75 Protein, NRH1b Protein, fullback Protein, nrh1 Protein, p75ntr Protein, tnfrsf16 Protein, p75NGFR Protein, nerve growth factor receptor Protein, neurotrophin receptor associated death domain Protein, nerve growth factor receptor S homeolog Protein, nerve growth factor receptor (TNFR superfamily, member 16) Protein, NGFR Protein, nradd Protein, Ngfr Protein, ngfr.S Protein

Hintergrund: NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
Synonyms: Gp80-LNGFR, p75 ICD, CD271, TNFRSF16

Molekulargewicht: 32-60 kDa, observed by reducing SDS-PAGE.

UniProt: P08138

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding