Thrombopoietin Protein (THPO) (AA 22-356)
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- Target Alle Thrombopoietin (THPO) Proteine anzeigen
- Thrombopoietin (THPO)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 22-356
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Spezies
- Maus
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Quelle
- CHO Cells
- Produktmerkmale
- ED50 < 2 ng /mL, measured in a proliferation assay using MO7e cells.
- Reinheit
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Thrombopoietin (THPO) (AA 22-195) protein (His-IF2DI Tag)
THPO Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thrombopoietin (THPO) (AA 23-195) protein (His tag)THPO Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Thrombopoietin (THPO) protein (His tag)THPO Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Thrombopoietin (THPO) (AA 1-349) protein (GST tag)THPO Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Thrombopoietin (THPO) proteinTHPO Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL..
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant murine Thrombopoietin (TPO) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, murine Thrombopoietin (TPO) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- Thrombopoietin (THPO)
- Andere Bezeichnung
- Thrombopoietin (TPO) (THPO Produkte)
- Synonyme
- MGDF Protein, MKCSF Protein, ML Protein, MPLLG Protein, THCYT1 Protein, TPO Protein, Mgdf Protein, Ml Protein, Mpllg Protein, Tpo Protein, Tpo1 Protein, Tpo2 Protein, Tpo3 Protein, Tpo4 Protein, tpo Protein, LOC100231762 Protein, thrombopoietin Protein, THPO Protein, Thpo Protein, thpo Protein
- Hintergrund
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Thrombopoietin (TPO), also known as C-mpl ligand, MGDF and Thpo, is a glycoprotein hormone belonging to the EPO/TPO family. It is expressed mainly in the liver, kidney and skeletal muscle. TPO binds and signals through MLP/C_MPL receptor. It stimulates the proliferation and maturation of megakaryocytes from their committed progenitor cells, and it regulates the production and circulation of platelets. TPO has also been reported to promote the apoptosis of hypoxia-sensitized neurons and to inhibit neuronal differentiation.
Synonyms: Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF - Molekulargewicht
- 30-80 kDa, observed by reducing SDS-PAGE.
- UniProt
- P40226
- Pathways
- JAK-STAT Signalweg, Hormone Activity
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