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TGFA Protein (AA 40-89)

TGFA Spezies: Human Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Produktnummer ABIN2018416
  • Target Alle TGFA Proteine anzeigen
    TGFA (Transforming Growth Factor, alpha (TGFA))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 40-89
    Spezies
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Quelle
    • 21
    • 4
    • 3
    • 2
    CHO Cells
    Produktmerkmale
    ED50 < 0.4 ng/mL, measured in a cell proliferation assay using 3T3 cells.
    Reinheit
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin-Niveau
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product TGFA Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Lyophilized recombinant Human TGF-alpha remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TGF-alpha Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Haltbarkeit
    6 months
  • Target
    TGFA (Transforming Growth Factor, alpha (TGFA))
    Andere Bezeichnung
    Transforming Growth Factor-alpha (TGF-Alpha) (TGFA Produkte)
    Synonyme
    TFGA Protein, LOC100009482 Protein, TGF alpha Protein, TGFA Protein, wa-1 Protein, wa1 Protein, RATTGFAA Protein, TGFAA Protein, NV15606 Protein, si:ch211-10e8.7 Protein, transforming growth factor alpha Protein, transforming growth factor alpha L homeolog Protein, transforming growth factor-alpha Protein, transforming growth factor, alpha Protein, TGFA Protein, TGF-A Protein, Tgfa Protein, tgfa.L Protein, LOC100121300 Protein, LOC100009150 Protein, tgfa Protein
    Hintergrund
    Protransforming Growth Factor-alpha (TGF-alpha), also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. ProTGF-alpha signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. It may function as either a membrane-bound ligand or a soluble ligand. Membrane-bound proTGF-alpha plays a role in cell-cell adhesion and juxtacrine stimulation of adjacent cells. The soluble form of the cytokine is released from the membrane-bound form by proteolytic cleavage and acts as a mitogen for cell proliferation.
    Synonyms: Transforming Growth Factor-alpha, Sacroma growth factor, TGF-type I, ETGF
    Molekulargewicht
    8-10 kDa, observed by reducing SDS-PAGE.
    UniProt
    P01135
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway
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