TGFA
Spezies: Ziege
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstituted in ddH2O or PBS at 100 μg/mL.
Buffer
Lyophilized after extensive dialysis against PBS.
Lagerung
-80 °C
Informationen zur Lagerung
Lyophilized recombinant Human TGF-alpha remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TGF-alpha Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
Protransforming Growth Factor-alpha (TGF-alpha), also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. ProTGF-alpha signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. It may function as either a membrane-bound ligand or a soluble ligand. Membrane-bound proTGF-alpha plays a role in cell-cell adhesion and juxtacrine stimulation of adjacent cells. The soluble form of the cytokine is released from the membrane-bound form by proteolytic cleavage and acts as a mitogen for cell proliferation. Synonyms: Transforming Growth Factor-alpha, Sacroma growth factor, TGF-type I, ETGF