TWEAK Protein (AA 99-249)
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- Target Alle TWEAK (TNFSF12) Proteine anzeigen
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 99-249
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Spezies
- Human
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Quelle
- CHO Cells
- Produktmerkmale
- ED50 < 1 ng/mL, measured in a cell cytotoxicity assay using HTB-38 (HT-29) cells.
- Reinheit
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product TNFSF12 Protein
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Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 43-249) protein (Fc Tag)
TNFSF12 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 106-249) protein (His-DYKDDDDK-Strep II Tag)TNFSF12 Spezies: Human Wirt: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 49-134) protein (GST tag)TNFSF12 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 1-134) protein (GST tag)TNFSF12 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant Human TWEAK remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TWEAK should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Andere Bezeichnung
- TWEAK (TNFSF12 Produkte)
- Synonyme
- APO3L Protein, DR3LG Protein, TWEAK Protein, Apo3l Protein, Dr3l Protein, Dr3lg Protein, Tweak Protein, TNF superfamily member 12 Protein, tumor necrosis factor (ligand) superfamily, member 12 Protein, TNFSF12 Protein, Tnfsf12 Protein
- Hintergrund
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TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its receptor TWEAKR induces NF-kappaB activation, chemokine secretion and apoptosis in certain cell types. TWEAK has also been reported to promote endothelial cell proliferation and migration, thus serving as a regulator of angiogenesis.
Synonyms: TNF-related weak inducer of apoptosis, TNFSF12, DR3LG, Apo3-Ligand - Molekulargewicht
- 20-22 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q4ACW9
- Pathways
- Apoptose
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