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Thyroperoxidase Protein (full length)

TPO Spezies: Human Wirt: Insect cells (Sf9) Recombinant > 95 % pure WB, ELISA
Produktnummer ABIN2132174
  • Target Alle Thyroperoxidase (TPO) Proteine anzeigen
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    full length
    Spezies
    • 8
    • 4
    • 2
    Human
    Quelle
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Insect cells (Sf9)
    Applikation
    Western Blotting (WB), ELISA
    Produktmerkmale
    Purified recombinant Human Thyroid Peroxidase protein
    Expression System: Sf-9 insect cells
    Aufreinigung
    Proprietary chromatographic technique
    Reinheit
    > 95 % pure
    Top Product
    Discover our top product TPO Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    16 mM HEPES, pH 7.6, with 166 mM NaCl, 0.06 mM Kl and 20 % glycerol.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Target
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Andere Bezeichnung
    Thyroid Peroxidase (TPO Produkte)
    Synonyme
    MSA Protein, TDH2A Protein, TPX Protein, TPO Protein, msa Protein, tpx Protein, xtpo Protein, LOC100218312 Protein, thyroid peroxidase Protein, TPO Protein, Tpo Protein, tpo Protein, LOC100547103 Protein
    Hintergrund
    Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx. 100 kDa molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3.
    Alternative Names: TPX protein, MSA protein, TPO protein
    Molekulargewicht
    101 kDa
    Pathways
    Thyroid Hormone Synthesis
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