BMP5 Protein
BMP5
Spezies: Human
Wirt: CHO Cells
Recombinant
< 95 % by SDS-PAGE gel and HPLC analyses.
Active
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- Target Alle BMP5 Proteine anzeigen
- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- CHO Cells
- Sequenz
- AANKRKNQNR NKSSSHQDSS RMSSVGDYNT SEQKQACKKH ELYVSFRDLG WQDWIIAPEG YAAFYCDGEC SFPLNAHMNA TNHAIVQTLV HLMFPDHVPK PCCAPTKLNA ISVLYFDDSS NVILKKYRNM VVRSCGCH
- Produktmerkmale
- Biological activity was determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0-2.0 μg/mL.
- Reinheit
- < 95 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin-Niveau
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product BMP5 Protein
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Bone Morphogenetic Protein 5 (BMP5) (AA 317-454) protein
BMP5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Bone Morphogenetic Protein 5 (BMP5) (AA 1-454) protein (GST tag)BMP5 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Handhabung
- As with any protein, exposing BMP-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BMP-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Haltbarkeit
- 24 months
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- Target
- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
- Andere Bezeichnung
- BMP-5 (BMP5 Produkte)
- Hintergrund
- TGF-beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.
- Gen-ID
- 653
- NCBI Accession
- NP_066551
- OMIM
- 10835091
- UniProt
- P22003
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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