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Calreticulin Protein (CALR) (AA 18-417)
CALR
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
~90 %
WB, ELISA, MS
Produktnummer ABIN2468306
Produktdetails
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Target
Alle Calreticulin (CALR) Proteine anzeigen
Calreticulin (CALR)
Protein-Typ
Recombinant
Proteineigenschaft
AA 18-417
Spezies
Alle Spezies für Calreticulin Proteine
Human
Quelle
Alle Expressionssysteme für Calreticulin Proteine
Escherichia coli (E. coli)
Applikation
Western Blotting (WB), ELISA, Mass Spectrometry (MS)
Reinheit
~90 %
Top Product
Discover our top product CALR Protein
Alternativen
(anzeigen)
Anwendungsinformationen
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Applikationshinweise
This recombinant protein can be used for WB, ELISA, MS.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Buffer
10 mM Tris, pH 8.0, 0.002 % NaN, 3 mM NaCl, 2.5 mM
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Lagerung
-80 °C
Informationen zur Lagerung
Store in working aliquots at -70 °C.
Antigendetails
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Target
Calreticulin (CALR)
Andere Bezeichnung
CALR (CALR Produkte )
Synonyme
CRT Protein, RO Protein, SSA Protein, cC1qR Protein, crc Protein, crt Protein, Calregulin Protein, CG9429 Protein, Clr Protein, Dmel\\CG9429 Protein, anon-EST:Liang-2.11 Protein, anon-EST:Liang-2.17 Protein, anon-EST:fe3D7 Protein, clone 2.11 Protein, clone 2.17 Protein, eth Protein, potp Protein, cc1qr Protein, ssa Protein, NV19007 Protein, CRP55 Protein, ERp60 Protein, HACBP Protein, CHOT1 Protein, CHT1 Protein, CT1 Protein, AA589632 Protein, CRTR Protein, Creat Protein, CCDS1 Protein, calrl2 Protein, fc66d10 Protein, wu:fc66d10 Protein, wu:fj50c03 Protein, zgc:66153 Protein, calreticulin Protein, calreticulin L homeolog Protein, Calreticulin Protein, putative calreticulin Protein, solute carrier family 6 member 8 Protein, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Protein, CALR Protein, calr.L Protein, Crt Protein, crt Protein, CRT Protein, Calr Protein, calr Protein, LMJF_31_2600 Protein, Crc Protein, Slc6a8 Protein, SLC6A8 Protein, LOC8269812 Protein
Hintergrund
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Molekulargewicht
46 kDa (Calculated)
Gen-ID
811
NCBI Accession
NP_004334
OMIM
4757900
UniProt
P27797
Pathways
Retinoic Acid Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Nuclear Hormone Receptor Binding , ER-Nucleus Signaling , Unfolded Protein Response
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