TMPRSS15 Protein

Produktnummer ABIN2468372

Dieses Recombinant TMPRSS15-Protein wird in CHO Cells exprimiert.

Kurzübersicht für TMPRSS15 Protein (ABIN2468372)

Target: TMPRSS15 (Transmembrane Protease, serine 15 (TMPRSS15))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: CHO Cells

Reinheit: < 90 % by SDS-PAGE gel and HPLC analyses.

Produktdetails

Sequenz: Heavy chain: LTIKESQRG AALGQSHEAR ATFKITSGVT YNPNLQDKLS VDFKVLAFDL QQMIDEIFLS SNLKNEYKNS RVLQFENGSI IVVFDLFFAQ WVSDQNVKEE LIQGLEANKS SQLVTFHIDL NSVDILDKLT TTSHLATPGN VSIECLPGSS PCTDALTCIK ADLFCDGEVN CPDGSDEDNK MCATVCDGRF LLTGSSGSFQ ATHYPKPSET SVVCQWIIRV NQGLSIKLSF DDFNTYYTDI LDIYEGVGSS KILRASIWET NPGTIRIFSN QVTATFLIES DESDYVGFNA TYTAFNSSEL NNYEKINCNF EDGFCFWVQD LNDDNEWERI QGSTFSPFTG PNFDHTFGNA SGFYISTPTG PGGRQERVGL LSLPLDPTLE PACLSFWYHM YGENVHKLSI NISNDQNMEK TVFQKEGNYG DNWNYGQVTL NETVKFKVAF NAFKNKILSD IALDDISLTY GICNGSLYPE PTLVPTPPPE LPTDCGGPFE LWEPNTTFSS TNFPNSYPNL AFCVWILNAQ KGKNIQLHFQ EFDLENINDV VEIRDGEEAD SLLLAVYTGP GPVKDVFSTT NRMTVLLITN DVLARGGFKA NFTTGYHLGI P EPCKADHF QCKNGECVPL VNLCDGHLHC EDGSDEADCV RFFNGTTNNN GLVRFRIQSI WHTACAENWT TQISNDVCQL LGLGSGNSSK PIFSTDGGPF VKLNTAPDGH LILTPSQQCL QDSLIRLQCN HKSCGKKLAA QDITPK Light Chain: IVGGSNAKE GAWPWVVGLY YGGRLLCGAS LVSSDWLVSA AHCVYGRNLE PSKWTAILGL HMKSNLTSPQ TVPRLIDEIV INPHYNRRRK DNDIAMMHLE FKVNYTDYIQ PICLPEENQV FPPGRNCSIA GWGTVVYQGT TANILQEADV PLLSNERCQQ QMPEYNITEN MICAGYEEGG IDSCQGDSGG PLMCQENNRW FLAGVTSFGY KCALPNRPGV YARVSRFTEW IQSFLH

Produktmerkmale: Sequentially cleaves carboxyl side of D-D-D-D-K.

Endotoxin-Niveau: Endotoxin level is less than 0.2 ng per μg (2EU/μg).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Handhabung: As with any protein, exposing Enterokinase recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Lagerung: -20 °C

Informationen zur Lagerung: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Enterokinase stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Haltbarkeit: 24 months

Antigendetails

Target: TMPRSS15 (Transmembrane Protease, serine 15 (TMPRSS15))

Andere Bezeichnung: Enterokinase

Hintergrund: Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Enterokinase sequentially cleaves carboxyl side of D-D-D-D-K. Human Enterokinase is expressed as a linear 1019 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of Enterokinase, which consists of two polypeptide chains (heavy chain and light chain) held together by a single disulfide bond, resulting in formation of a biologically active heterodimer. The heavy chain consists of 784 amino acid residues, and the light consists of 235 amino acid residues.

Gen-ID: 5651

NCBI Accession: NP_002763

OMIM: 223942069

UniProt: P98073