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GDF5 Protein

GDF5 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant < 98 % by SDS-PAGE gel and HPLC analyses. Active
Produktnummer ABIN2468474
  • Target Alle GDF5 Proteine anzeigen
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 7
    • 3
    • 2
    Maus
    Quelle
    • 11
    • 1
    Escherichia coli (E. coli)
    Sequenz
    APLANRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
    Produktmerkmale
    Endotoxin level is less than 0.1 ng per μg (1EU/μg).
    Reinheit
    < 98 % by SDS-PAGE gel and HPLC analyses.
    Endotoxin-Niveau
    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
    Top Product
    Discover our top product GDF5 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Handhabung
    As with any protein, exposing GDF-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
    Haltbarkeit
    24 months
  • Target
    GDF5 (Growth Differentiation Factor 5 (GDF5))
    Andere Bezeichnung
    GDF-5 (GDF5 Produkte)
    Synonyme
    CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein
    Hintergrund
    GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Grebe Syndrome, which is characterized by short stature, extra digits, short and deformed extremities, and in Hunter-Thompson type dwarfism. The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino-acid signal peptide and a 348 amino-acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant murine GDF-5 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids.
    Gen-ID
    8200
    NCBI Accession
    NP_000548
    OMIM
    4503969
    UniProt
    P43026
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