GDF7 Protein

Produktnummer ABIN2468476

Produktdetails

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR

Produktmerkmale: Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.

Reinheit: < 98 % by SDS-PAGE gel and HPLC analyses.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Handhabung: As with any protein, exposing GDF-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Lagerung: -20 °C

Informationen zur Lagerung: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-7 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Haltbarkeit: 24 months

Antigendetails

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Andere Bezeichnung: GDF-7 (GDF7 Produkte)

Synonyme: bmp12 Protein, gdf-7 Protein, gdf16 Protein, gdf16-A Protein, BMP12 Protein, GDF6/7 Protein, growth differentiation factor 7 S homeolog Protein, growth differentiation factor 7 Protein, gdf7.S Protein, GDF7 Protein, Gdf7 Protein

Hintergrund: GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue. Recombinant human GDF-7 is a 28 kDa disulfide linked homodimer containing two 129 amino acid residues.

Gen-ID: 151449

NCBI Accession: NP_878248

OMIM: 61835232

UniProt: Q7Z4P5

Pathways: Tube Formation