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IL-34 Protein

IL34 Spezies: Human Wirt: HEK-293 Cells Recombinant < 95 % by SDS-PAGE gel and HPLC analyses. Active
Produktnummer ABIN2468681
  • Target Alle IL-34 (IL34) Proteine anzeigen
    IL-34 (IL34) (Interleukin 34 (IL34))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 9
    • 4
    • 3
    • 1
    Human
    Quelle
    • 6
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    Sequenz
    NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH
    Produktmerkmale
    Endotoxin level is less than 0.1 ng per μg (1EU/μg).
    Reinheit
    < 95 % by SDS-PAGE gel and HPLC analyses.
    Endotoxin-Niveau
    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
    Top Product
    Discover our top product IL34 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Handhabung
    As with any protein, exposing IL-34 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-34 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
    Haltbarkeit
    24 months
  • Target
    IL-34 (IL34) (Interleukin 34 (IL34))
    Andere Bezeichnung
    IL-34 (IL34 Produkte)
    Synonyme
    C16orf77 Protein, IL-34 Protein, 2010004A03Rik Protein, AI593503 Protein, C18H16ORF77 Protein, interleukin 34 Protein, IL34 Protein, Il34 Protein
    Hintergrund
    IL-34 is a homodimeric cytokine that is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.
    Gen-ID
    146433
    NCBI Accession
    NP_001166242
    OMIM
    289666750
    UniProt
    Q6ZMJ4
    Pathways
    RTK Signalweg
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