S100A6 Protein

Produktnummer ABIN2566904

Recombinant S100A6-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für S100A6 Protein (ABIN2566904)

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Western Blotting (WB)

Reinheit: >95 % as determined by SDS-PAGE.

Produktdetails

Produktmerkmale:

The bio-activity of S100A6 was determined by its binding ability with human CEACAM3 protein in the presence of 100 mM CaCl2.

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB. For research use only.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -80 °C,-20 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Andere Bezeichnung: S100A6

Hintergrund: S100 calcium binding protein A6 (S100-A6) is also kown as 2A9, 5B10, CABP, CACY and PRA, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100A6 may function in stimulation of Ca2+ -dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. S100A6 has been shown to interact with S100B and SUGT1.

Molekulargewicht: 10.2 kDa

Gen-ID: 6277

NCBI Accession: NP_055439

UniProt: P06703

Pathways: S100 Proteine