BRDT Protein (AA 21-137) (His tag,DYKDDDDK Tag)

Produktnummer ABIN2669698

Produktdetails

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-137

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BRDT Protein ist gelabelt mit His tag,DYKDDDDK Tag.

Applikation: Binding Studies (Bind), Screening Assay (ScA)

Produktmerkmale: The peptide corresponding to amino acids 21-137 that contains the bromodomain sequences of BRDT (accession number NP_001717.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20 kDa. It shows binding specificity for acetylated H2BK12/15, H3K9/14/18/23, H4K12, H4K5/8, H4K8/12, H4K12/16, H4K5/12, H4K5/8/12/16 and H4K5/8/12/16.

Anwendungsinformationen

Applikationshinweise: Recombinant BRDT (21-137) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -80 °C

Informationen zur Lagerung: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.

Antigendetails

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Andere Bezeichnung: BRDT (BRDT Produkte)

Synonyme: BRD6 Protein, CT9 Protein, 7420412D09Rik Protein, Brd6 Protein, Fsrg3 Protein, BRDT Protein, MGC151933 Protein, fi25h02 Protein, si:dkeyp-85h7.3 Protein, wu:fi25h02 Protein, bromodomain testis associated Protein, bromodomain, testis-specific Protein, bromodomain, testis-specific L homeolog Protein, BRDT Protein, Brdt Protein, brdt.L Protein, brdt Protein

Hintergrund: BRDT is similar to the RING3 protein family. It possesses two bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain functions as a 'reader' of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets.

Molekulargewicht: 20 kDa