Claudin 19 Protein (CLDN19) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target Alle Claudin 19 (CLDN19) Proteine anzeigen
- Claudin 19 (CLDN19)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 2
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Claudin 19 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Claudin-19 / CLDN19 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CLDN19 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Claudin 19 (CLDN19)
- Andere Bezeichnung
- Claudin-19,cldn19 (CLDN19 Produkte)
- Synonyme
- HOMG5 Protein, claudin-19 Protein, zgc:112141 Protein, claudin 19 Protein, claudin 19 S homeolog Protein, CLDN19 Protein, Cldn19 Protein, cldn19.S Protein, cldn19 Protein
- Hintergrund
- The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
- Molekulargewicht
- 21.9 kDa
- NCBI Accession
- NP_001116867
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
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