CCNDBP1 Protein (His tag)

Produktnummer ABIN2713325

Produktdetails

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CCNDBP1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CCNDBP1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 100 mM Arg. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Andere Bezeichnung: Ccndbp1 (CCNDBP1 Produkte)

Synonyme: CCNDBP1 Protein, dip1 Protein, gcip Protein, DIP1 Protein, GCIP Protein, HHM Protein, AU022347 Protein, Maid Protein, SECC-8 Protein, SSEC-8 Protein, cyclin D1 binding protein 1 Protein, cyclin D-type binding-protein 1 Protein, CCNDBP1 Protein, ccndbp1 Protein, Ccndbp1 Protein

Hintergrund: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.

Molekulargewicht: 40.3 kDa

NCBI Accession: NP_036274