ALOX5 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714585

Produktdetails

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ALOX5 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ALOX5 / LOG5 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Andere Bezeichnung: Alox5,log5 (ALOX5 Produkte)

Synonyme: 5-LO Protein, 5-LOX Protein, 5LPG Protein, LOG5 Protein, 5LO Protein, 5LX Protein, AI850497 Protein, F730011J02 Protein, LOX5A Protein, si:dkey-194n13.2 Protein, lox5 Protein, arachidonate 5-lipoxygenase Protein, arachidonate 5-lipoxygenase a Protein, Arachidonate 5-lipoxygenase Protein, ALOX5 Protein, Alox5 Protein, alox5a Protein, AFUA_4G02770 Protein, AOR_1_1362014 Protein, lox5 Protein

Hintergrund: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 77.8 kDa

NCBI Accession: NP_000689