ACTN1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
-
- Target Alle ACTN1 Proteine anzeigen
- ACTN1 (Actinin, alpha 1 (ACTN1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 2
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses ACTN1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
-
- Recombinant human Alpha-actinin-1 / ACTN1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ACTN1 Protein
-
-
- Applikationshinweise
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
-
The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- ACTN1 (Actinin, alpha 1 (ACTN1))
- Andere Bezeichnung
- alpha-Actinin-1,actn1 (ACTN1 Produkte)
- Synonyme
- ACTN1 Protein, actinin Protein, BDPLT15 Protein, 3110023F10Rik Protein, Actn1a Protein, actinin alpha 1 Protein, actinin, alpha 1 Protein, actinin alpha 1 L homeolog Protein, ACTN1 Protein, actn1 Protein, Actn1 Protein, actn1.L Protein
- Hintergrund
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 102.9 kDa
- NCBI Accession
- NP_001093
- Pathways
- Cell-Cell Junction Organization
-