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APOE Protein
APOE
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Produktnummer ABIN2714831
Produktdetails
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Target
Alle APOE Proteine anzeigen
APOE
(Apolipoprotein E (APOE))
Protein-Typ
Recombinant
Spezies
Alle Spezies für APOE Proteine
Human
Quelle
Alle Expressionssysteme für APOE Proteine
Escherichia coli (E. coli)
Applikation
Antibody Production (AbP), Standard (STD)
Produktmerkmale
Recombinant human Apolipoprotein E / Apo E protein expressed in E. coli. Produced with end-sequenced ORF clone
Reinheit
> 90 % as determined by SDS-PAGE and Coomassie blue staining
Endotoxin-Niveau
Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Recombinant human proteins can be used for: Native antigens for optimized antibody production Positive controls in ELISA and other antibody assays
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
Handhabung
Resuspend the protein in the desired concentration in proper buffer
Lagerung
-80 °C
Informationen zur Lagerung
Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Antigendetails
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Target
APOE
(Apolipoprotein E (APOE))
Andere Bezeichnung
Apolipoprotein E,apo E (APOE Produkte )
Synonyme
ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein
Hintergrund
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Molekulargewicht
34.3 kDa
NCBI Accession
NP_000032
Pathways
Regulation of Cell Size , Lipid Metabolism
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