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BCL2A1 Protein (Transcript Variant 2)

BCL2A1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715200
  • Target Alle BCL2A1 Proteine anzeigen
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 6
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Bcl-2-like 5 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product BCL2A1 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    20 mM Phosphate buffer, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 10 % Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
    Andere Bezeichnung
    Bcl-2-Like 5 (BCL2A1 Produkte)
    Synonyme
    ACC-1 Protein, ACC-2 Protein, BCL2L5 Protein, BFL1 Protein, GRS Protein, HBPA1 Protein, Bcl2a1d Protein, BCL2A1 Protein, BCL2 related protein A1 Protein, BCL2-related protein A1 Protein, BCL2A1 Protein, Bcl2a1 Protein
    Hintergrund
    This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    18.5 kDa
    NCBI Accession
    NP_001108207
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