Fibrillarin Protein (FBL) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2720913

Produktdetails

Target: Fibrillarin (FBL)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Fibrillarin Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human FBL protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Fibrillarin (FBL)

Andere Bezeichnung: Fbl (FBL Produkte)

Synonyme: FIB Protein, FLRN Protein, RNU3IP1 Protein, wu:fb37g12 Protein, zgc:56145 Protein, zgc:77130 Protein, FBL Protein, AL022665 Protein, CG9888 Protein, Dmel\\CG9888 Protein, Fibri Protein, GCR-6 Protein, GCR6 Protein, Pen59C5 Protein, fib Protein, pen59C5 Protein, MGC76139 Protein, fbl Protein, fibrillarin Protein, Fibrillarin Protein, putative fibrillarin Protein, fibrillarin S homeolog Protein, FBL Protein, fbl Protein, Fbl Protein, Fib Protein, fib1 Protein, LMJF_19_0100 Protein, fbl.S Protein

Hintergrund: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

Molekulargewicht: 33.6 kDa

NCBI Accession: NP_001427

Pathways: Ribonucleoside Biosynthetic Process