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FGF5 Protein (Transcript Variant 2)

FGF5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Produktnummer ABIN2721093
  • Target Alle FGF5 Proteine anzeigen
    FGF5 (Fibroblast Growth Factor 5 (FGF5))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 7
    • 1
    • 1
    • 1
    Human
    Quelle
    • 5
    • 3
    • 2
    Escherichia coli (E. coli)
    Applikation
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human FGF5 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is less than or equal to 0.5 ng/ml, corresponding to a specific activity of > 2 x 10^6 units/mg.
    Top Product
    Discover our top product FGF5 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handhabung
    Resuspend the protein in the desired concentration in proper buffer
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FGF5 (Fibroblast Growth Factor 5 (FGF5))
    Andere Bezeichnung
    Fgf5 (FGF5 Produkte)
    Synonyme
    FGF5 Protein, HBGF-5 Protein, Smag-82 Protein, Fgf-5 Protein, angora Protein, go Protein, FGF-5 Protein, fibroblast growth factor 5 Protein, FGF5 Protein, fgf5 Protein, Fgf5 Protein
    Hintergrund
    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Molekulargewicht
    27.6 kDa
    NCBI Accession
    NP_004455
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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