Fibromodulin Protein (FMOD) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2721165

Produktdetails

Target: Fibromodulin (FMOD)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Fibromodulin Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Fibromodulin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Adini, Adini, Bazinet, Watnick, Bielenberg, DAmato: "Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2014) (PubMed).

Antigendetails

Target: Fibromodulin (FMOD)

Andere Bezeichnung: Fibromodulin (FMOD Produkte)

Synonyme: FMOD Protein, AI131919 Protein, AU041740 Protein, SLRR2E Protein, LOC100286414 Protein, sc:d0415 Protein, si:dkey-31j12.4 Protein, LOC100229381 Protein, FM Protein, fibromodulin Protein, fibromodulin b Protein, FMOD Protein, Fmod Protein, LOC100286414 Protein, fmodb Protein

Hintergrund: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 41.2 kDa

NCBI Accession: NP_002014

Pathways: Glycosaminoglycan Metabolic Process