IDH3G Protein (His tag)

Produktnummer ABIN2723871

Produktdetails

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses IDH3G Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Isocitric dehydrogenase gamma / IDH3G (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Andere Bezeichnung: Isocitric Dehydrogenase Gamma,idh3g (IDH3G Produkte)

Synonyme: H-IDHG Protein, MGC83400 Protein, wu:fa01b02 Protein, wu:fc88f06 Protein, h-idhg Protein, IDH Protein, isocitrate dehydrogenase 3 (NAD(+)) gamma Protein, isocitrate dehydrogenase 3 (NAD+) gamma S homeolog Protein, isocitrate dehydrogenase 3 (NAD+) gamma Protein, isocitrate dehydrogenase 3 (NAD+), gamma Protein, isocitrate dehydrogenase 3 (NAD), gamma Protein, IDH3G Protein, idh3g.S Protein, idh3g Protein, Idh3g Protein

Hintergrund: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Molekulargewicht: 38.8 kDa

NCBI Accession: NP_004126