KIRREL2 Protein (His tag)

Produktnummer ABIN2724260

Produktdetails

Target: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses KIRREL2 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human KIRREL2 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Andere Bezeichnung: Kirrel2 (KIRREL2 Produkte)

Synonyme: nlg1 Protein, neph3 Protein, filtrin Protein, FILTRIN Protein, NEPH3 Protein, NLG1 Protein, C330019F22Rik Protein, cb33 Protein, kirrel3 Protein, sb:cb33 Protein, si:dkey-29g23.1 Protein, wu:fb74e02 Protein, kirre like nephrin family adhesion molecule 2 Protein, kin of IRRE like 2 (Drosophila) Protein, kirre like nephrin family adhesion molecule 3, like Protein, kirrel2 Protein, KIRREL2 Protein, Kirrel2 Protein, kirrel3l Protein

Hintergrund: This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.

Molekulargewicht: 66.9 kDa

NCBI Accession: NP_115499