Lamin B2 Protein (LMNB2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724479

Produktdetails

Target: Lamin B2 (LMNB2)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Lamin B2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Lamin-B2 (LMNB2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Lamin B2 (LMNB2)

Andere Bezeichnung: Lamin-b2 (Lmnb2) (LMNB2 Produkte)

Synonyme: lmnb2-a Protein, LMNB2 Protein, lmn2 Protein, lamb2 Protein, Lamin-L(II) Protein, LOC100136040 Protein, im:7142331 Protein, lamin Protein, wu:fb94e05 Protein, wu:fb95e12 Protein, wu:fc15d06 Protein, wu:fc49h03 Protein, lamin-b2 Protein, lmnb2 Protein, LAMB2 Protein, LMN2 Protein, RGD1563803 Protein, lamin B2 S homeolog Protein, lamin B2 Protein, lamin B2 L homeolog Protein, lmnb2.S Protein, LMNB2 Protein, lmnb2 Protein, lmnb2.L Protein, Lmnb2 Protein

Hintergrund: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Molekulargewicht: 67.5 kDa

NCBI Accession: NP_116126

Pathways: Apoptose, Caspase Kaskade in der Apoptose