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MAPKAP Kinase 3 Protein (Myc-DYKDDDDK Tag)

MAPKAPK3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
Produktnummer ABIN2725454
  • Target Alle MAPKAP Kinase 3 (MAPKAPK3) Proteine anzeigen
    MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 7
    • 1
    • 1
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses MAPKAP Kinase 3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human MAPKAP Kinase-3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Biological Activity Comment
    MAPKAPK3 activity verified in a biochemical assay:,MAPKAPK3 activity verified in a biochemical assay:
    Top Product
    Discover our top product MAPKAPK3 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    > 50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
    Andere Bezeichnung
    Mapkap Kinase-3 (MAPKAPK3 Produkte)
    Synonyme
    3PK Protein, MAPKAP-K3 Protein, MAPKAP3 Protein, MAPKAPK-3 Protein, MK-3 Protein, AI874665 Protein, MK3 Protein, MapkKapk3 Protein, MAPKAPK3 Protein, mapkapk3 Protein, MGC154360 Protein, 3pk Protein, mapkap3 Protein, zgc:158342 Protein, mitogen-activated protein kinase-activated protein kinase 3 Protein, mitogen-activated protein kinase-activated protein kinase 3 S homeolog Protein, MAPKAPK3 Protein, Mapkapk3 Protein, mapkapk3.S Protein, mapkapk3 Protein
    Hintergrund
    This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.
    Molekulargewicht
    42.8 kDa
    NCBI Accession
    NP_004626
    Pathways
    MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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