MAML1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725542

Produktdetails

Target: MAML1 (Mastermind-Like 1 (MAML1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MAML1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Mastermind-Like Protein 1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MAML1 (Mastermind-Like 1 (MAML1))

Andere Bezeichnung: Mastermind-Like Protein 1 (MAML1 Produkte)

Synonyme: mam1 Protein, mam-1 Protein, xmam1 Protein, MAML1 Protein, AI644666 Protein, AW743257 Protein, D930008C07Rik Protein, Mam-1 Protein, Mam1 Protein, mKIAA0200 Protein, mastermind like transcriptional coactivator 1 L homeolog Protein, mastermind like transcriptional coactivator 1 Protein, mastermind like 1 (Drosophila) Protein, mastermind-like transcriptional coactivator 1 Protein, maml1.L Protein, MAML1 Protein, Maml1 Protein

Hintergrund: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Molekulargewicht: 107.9 kDa

NCBI Accession: NP_055572

Pathways: Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development