NFKBIB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target Alle NFKBIB Proteine anzeigen
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 2
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses NFKBIB Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFKBIB Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- Andere Bezeichnung
- Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (Nfkbib) (NFKBIB Produkte)
- Synonyme
- NFKBIB Protein, IKB-beta Protein, IKappaBbeta Protein, IkB Protein, IkBb Protein, IKBB Protein, TRIP9 Protein, NFKB inhibitor beta Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Protein, NFKBIB Protein, Nfkbib Protein
- Hintergrund
- Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. [UniProtKB/Swiss-Prot Function]
- Molekulargewicht
- 32.6 kDa
- NCBI Accession
- NP_001001716
- Pathways
- NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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