Nyctalopin Protein (NYX) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2727840

Produktdetails

Target: Nyctalopin (NYX)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Nyctalopin Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Nyctalopin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Nyctalopin (NYX)

Andere Bezeichnung: Nyctalopin (NYX Produkte)

Synonyme: MGC84276 Protein, CLRP Protein, CSNB1 Protein, CSNB1A Protein, CSNB4 Protein, NBM1 Protein, CLNP Protein, nob Protein, RGD1561300 Protein, nyctalopin Protein, nyctalopin L homeolog Protein, uncharacterized LOC491837 Protein, NYX Protein, nyx.L Protein, LOC491837 Protein, nyx Protein, Nyx Protein

Hintergrund: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

Molekulargewicht: 49.5 kDa

NCBI Accession: NP_072089