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PAK6 Protein (Transcript Variant 1)

PAK6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
Produktnummer ABIN2728179
  • Target Alle PAK6 Proteine anzeigen
    PAK6 (P21-Activated Kinase 6 (PAK6))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 4
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human PAK6 (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 90 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Specific activity was determined as 2,086 pmoles/min/μg, according to the Zlyte assay protocol
    Top Product
    Discover our top product PAK6 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PAK6 (P21-Activated Kinase 6 (PAK6))
    Andere Bezeichnung
    Pak6 (PAK6 Produkte)
    Synonyme
    PAK5 Protein, 4732456M09 Protein, pak6 Protein, si:ch211-158b22.3 Protein, p21 (RAC1) activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6b Protein, PAK6 Protein, Pak6 Protein, pak6b Protein
    Hintergrund
    This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    34.2 kDa
    NCBI Accession
    NP_064553
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