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PAK7 Protein (Transcript Variant 2)

PAK7 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
Produktnummer ABIN2728183
  • Target Alle PAK7 Proteine anzeigen
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 3
    • 1
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human PAK7 / PAK5 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 90 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Specific activity was determined as 4,199 pmoles/min/μg, according to the Zlyte assay protocol
    Top Product
    Discover our top product PAK7 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
    Andere Bezeichnung
    Pak7,pak5 (PAK7 Produkte)
    Synonyme
    PAK5 Protein, pak5 Protein, 2900083L08Rik Protein, 6430627N20 Protein, Pak5 Protein, PAK-5 Protein, PAK-7 Protein, p21 (RAC1) activated kinase 5 Protein, p21 (RAC1) activated kinase 5 L homeolog Protein, p21 protein (Cdc42/Rac)-activated kinase 7 Protein, p21 (RAC1) activated kinase 7 Protein, PAK5 Protein, pak5.L Protein, Pak7 Protein
    Hintergrund
    The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
    Molekulargewicht
    33.9 kda
    NCBI Accession
    NP_817127
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