PIM1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728984

Produktdetails

Target: PIM1 (Pim-1 Oncogene (PIM1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PIM1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PIM1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PIM1 (Pim-1 Oncogene (PIM1))

Andere Bezeichnung: Pim1 (PIM1 Produkte)

Synonyme: PIM Protein, Pim-1 Protein, PIM1 Protein, pim Protein, pim-1 Protein, pim3 Protein, Pim-1 proto-oncogene, serine/threonine kinase Protein, proviral integration site 1 Protein, Pim-1 proto-oncogene, serine/threonine kinase L homeolog Protein, PIM1 Protein, Pim1 Protein, pim1 Protein, pim1.L Protein

Hintergrund: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].

Molekulargewicht: 35.5 kDa

NCBI Accession: NP_002639

Pathways: Glycosaminoglycan Metabolic Process