PLA2G12B Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729072

Produktdetails

Target: PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PLA2G12B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PLA2G12B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))

Andere Bezeichnung: Pla2g12b (PLA2G12B Produkte)

Synonyme: wu:fb26d02 Protein, wu:fb99g06 Protein, wu:fc91d12 Protein, zgc:111897 Protein, zgc:56487 Protein, zgc:77746 Protein, MGC79728 Protein, GXIIB Protein, GXIIIsPLA2 Protein, PLA2G13 Protein, 2010002E04Rik Protein, Pla2g13 Protein, hlb218 Protein, phospholipase A2, group XIIB Protein, phospholipase A2 group XIIB Protein, pla2g12b Protein, PLA2G12B Protein, Pla2g12b Protein

Hintergrund: The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants.

Molekulargewicht: 21.5 kDa

NCBI Accession: NP_115951