RAD23B Protein (Myc-DYKDDDDK Tag)
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- Target Alle RAD23B Proteine anzeigen
- RAD23B (RAD23 Homolog B (RAD23B))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses RAD23B Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human RAD23B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RAD23B Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RAD23B (RAD23 Homolog B (RAD23B))
- Andere Bezeichnung
- Rad23b (RAD23B Produkte)
- Synonyme
- HHR23B Protein, HR23B Protein, P58 Protein, 0610007D13Rik Protein, AV001138 Protein, mHR23B Protein, p58 Protein, MGC107846 Protein, zgc:65951 Protein, RAD23 homolog B, nucleotide excision repair protein Protein, UV excision repair protein RAD23 homolog B Protein, RAD23 homolog B, nucleotide excision repair protein S homeolog Protein, RAD23B Protein, Rad23b Protein, rd23b Protein, rad23b Protein, rad23b.S Protein
- Hintergrund
- The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molekulargewicht
- 43 kDa
- NCBI Accession
- NP_002865
- Pathways
- DNA Reparatur
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