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Senataxin (SETX) protein (Myc-DYKDDDDK Tag)

SETX Spezies: Human Wirt: HEK-293T Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2731631
  • Target Alle Senataxin (SETX) Produkte
    Senataxin (SETX)
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 1
    HEK-293T Cells
    Aufreinigungstag / Konjugat
    Myc-DYKDDDDK Tag
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Senataxin (SETX) protein expressed in HEK293 cell.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris-HCl, pH 7.3, 100 mM glycine, and 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Senataxin (SETX)
    Abstract
    SETX Produkte
    Synonyme
    ALS4 Protein, SETX Protein, wu:fj92h09 Protein, AOA2 Protein, SCAR1 Protein, bA479K20.2 Protein, Als4 Protein, Sen1 Protein, AW060766 Protein, mKIAA0625 Protein, A130090N03 Protein, A930037J23Rik Protein, RGD1565575 Protein, senataxin Protein, SETX Protein, setx Protein, Setx Protein
    Hintergrund
    This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).
    Molekulargewicht
    57.8 kDa
    NCBI Accession
    NP_055861
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