SLC9A3R1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732190

Produktdetails

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SLC9A3R1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SLC9A3R1 / NHERF protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Wang, Qin, Zhu: "Expression of Na+/H+ exchanger regulatory factor 1 in autosomal-dominant polycystic kidney disease." in: The Journal of international medical research, Vol. 43, Issue 5, pp. 629-38, (2015) (PubMed).

Antigendetails

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Andere Bezeichnung: Slc9a3r1,nherf (SLC9A3R1 Produkte)

Synonyme: EBP50 Protein, NHERF Protein, NHERF-1 Protein, NHERF1 Protein, NPHLOP2 Protein, SLC9A3R1 Protein, cb895 Protein, slc9a3r2 Protein, wu:fd20a02 Protein, zgc:55541 Protein, zgc:77629 Protein, EBP-50 Protein, NHE-RF Protein, nherf Protein, nherf-1 Protein, nherf1 Protein, slc9a3r1 Protein, SLC9A3 regulator 1 Protein, microRNA 3615 Protein, solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a Protein, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 Protein, SLC9A3 regulator 1 S homeolog Protein, SLC9A3R1 Protein, MIR3615 Protein, slc9a3r1a Protein, Slc9a3r1 Protein, slc9a3r1.S Protein

Hintergrund: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009].

Molekulargewicht: 38.7 kDa

NCBI Accession: NP_004243

Pathways: Proton Transport, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interaktom