SPG20 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- Target Alle SPG20 Proteine anzeigen
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 4
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SPG20 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Spartin / SPG20 (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))
- Andere Bezeichnung
- Spartin,spg20 (SPG20 Produkte)
- Synonyme
- SPARTIN Protein, TAHCCP1 Protein, AI840044 Protein, C79168 Protein, mKIAA0610 Protein, spartin Protein, Spg20 Protein, spg20a Protein, zgc:172059 Protein, spg20b Protein, zgc:153766 Protein, spartin Protein, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) Protein, spartin a Protein, spartin b Protein, SPART Protein, Spg20 Protein, Spart Protein, sparta Protein, spartb Protein
- Hintergrund
- This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
- Molekulargewicht
- 72.7 kDa
- NCBI Accession
- NP_001135766
- Pathways
- Regulation of Cell Size, SARS-CoV-2 Protein Interaktom
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