Stabilin 2 (STAB2) protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732748

Produktdetails

Target: Stabilin 2 (STAB2)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Myc-DYKDDDDK Tag

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Stabilin 2 / STAB2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Stabilin 2 (STAB2)

Andere Bezeichnung: Stabilin 2,stab2 (STAB2 Produkte)

Synonyme: FEEL2 Protein, FELE-2 Protein, FELL2 Protein, FEX2 Protein, HARE Protein, si:dkey-207j16.6 Protein, FEEL-2 Protein, FELL Protein, MFEEL-2 Protein, STAB-2 Protein, Hare Protein, hare Protein, stabilin 2 Protein, stabilin-2 Protein, STAB2 Protein, stab2 Protein, LOC100181366 Protein, Stab2 Protein

Hintergrund: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.

Molekulargewicht: 274.7 kDa

NCBI Accession: NP_060034

Pathways: Glycosaminoglycan Metabolic Process