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TYMS Protein (Myc-DYKDDDDK Tag)

TYMS Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2733654
  • Target Alle TYMS Proteine anzeigen
    TYMS (Thymidylate Synthetase (TYMS))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 4
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TYMS Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Thymidylate synthase (TS) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TYMS Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TYMS (Thymidylate Synthetase (TYMS))
    Andere Bezeichnung
    Thymidylate Synthase (Ts) (TYMS Produkte)
    Synonyme
    FN1 Protein, ECK2823 Protein, JW2795 Protein, ts Protein, Ts Protein, HST422 Protein, TMS Protein, TS Protein, thymidylate synthetase Protein, contains intron in T4 phage Protein, ThyE Protein, thymidylate synthase Protein, thymidylate synthetase L homeolog Protein, TYMS Protein, thyA Protein, td Protein, thyE Protein, DDA3937_RS04960 Protein, tyms.L Protein, XBJ1_RS15770 Protein, EAMY_RS20680 Protein, Tyms Protein
    Substanzklasse
    Viral Protein
    Hintergrund
    Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
    Molekulargewicht
    35.5 kDa
    NCBI Accession
    NP_001062
    Pathways
    Mitotic G1-G1/S Phases
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