Mps1 Protein (TTK) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734513

Produktdetails

Target: Mps1 (TTK)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Mps1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human TTK protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Mps1 (TTK)

Andere Bezeichnung: Ttk (TTK Produkte)

Synonyme: CT96 Protein, ESK Protein, MPH1 Protein, MPS1 Protein, MPS1L1 Protein, PYT Protein, AL022661 Protein, Esk1 Protein, Mps1 Protein, esk Protein, mps1 Protein, ncp Protein, Ttk protein kinase Protein, TTK protein kinase Protein, ttk protein kinase Protein, Ttk Protein, TTK Protein, ttk Protein

Hintergrund: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 96.9 kDa

NCBI Accession: NP_003309