JAK3 Protein (Myc-DYKDDDDK Tag)
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- Target Alle JAK3 Proteine anzeigen
- JAK3 (Janus Kinase 3 (JAK3))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses JAK3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Tyrosine-protein kinase JAK3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product JAK3 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- JAK3 (Janus Kinase 3 (JAK3))
- Andere Bezeichnung
- Tyrosine-Protein Kinase Jak3 (JAK3 Produkte)
- Synonyme
- JAK-3 Protein, JAK3_HUMAN Protein, JAKL Protein, L-JAK Protein, LJAK Protein, fae Protein, wil Protein, RATJAK3 Protein, JAK Protein, Janus kinase 3 Protein, JAK3 Protein, Jak3 Protein
- Hintergrund
- The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
- Molekulargewicht
- 124.9 kDa
- NCBI Accession
- NP_000206
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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